If you're the "I never read the instructions" type, you can download SmugMug's MacDaddy standalone app here and dive right in! Prefer to play it safe? Read on.
Find the options.
The first time you click the add photos button? and select a gallery, you'll see this:
The Simple choice is a good one, and works well for both Windows and Mac users. You'll find more info about it on this help page.
Got skills? You can upload directly from iPhoto, Aperture, and Lightroom as well. You will find the links to these apps on the uploading page.
Pssst! Batman uses MacDaddy.
Click MacDaddy.
You'll be asked to save a file. When you open it, you'll see a green smuggy that you can drag right into your Applications folder.
Open 'er up and enter your SmugMug login info.

Drag and drop photos into the files tab, or click +.

Select a Destination Gallery (or create one) and click Upload.
Have photos in iPhoto? We have a tab for you.
Check the boxes, select destination galleries, click Upload.
Tip: Send each iPhoto album to a different SmugMug gallery, all at the same time!